反应详情

Ethyl 3-methyl-5-(4-methyl-morpholin-2-ylmethoxy)-benzofuran-2-carboxylate (0.12 mmol) was dissolved in 300 μl of tetrahydrofuran. Then 300 μl of a 1.0 M solution of lithium hydroxide were added and the mixture stirred at room temperature for 3 hours. The tetrahydrofuran was removed under vacuo and the water eliminated by lyophilisation to yield the tilted compound as a white solid: m/z=304 in MS ES−.

1. customThe tetrahydrofuran was removed under vacuo