反应详情

A mixture of 3-(4-fluoro-phenyl)-2-isopropyl-7,8-dihydro-2H-1,2,6-triaza-azulene-6-carboxylic acid benzyl ester (0.2 g, 0.49 mmol) and 10% Pd/C (20 mg) in isopropanol (20 mL) was subjected to H2 (45 psi) at rt for 16 h. The mixture was filtered and the filtrate was concentrated. The residue was purified by FCC to give the title compound.

1. filtrationThe mixture was filtered
2. concentrationthe filtrate was concentrated
3. customThe residue was purified by FCC