Hydrochloric Acid → N,N-dimethyl-[6-(4-heptylbenzoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine hydrochloride

HRID 611133Notes

Reaction equation

HRID 611133 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:28][C:8]2[CH2:9][N:10]([C:13](=[O:27])[C:14]3[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])=[CH:16][CH:15]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3].[ClH:29]>CO.C(OCC)(=O)C>[ClH:29].[CH3:1][N:2]([CH2:4][C:5]1[O:28][C:8]2[CH2:9][N:10]([C:13](=[O:27])[C:14]3[CH:15]=[CH:16][C:17]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])=[CH:18][CH:19]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 19600030N,N-dimethyl-[6-(4-heptylbenzoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine

Product 1

HCID 19600029N,N-dimethyl-[6-(4-heptylbenzoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine hydrochloride

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

N,N-Dimethyl-[6-(4-heptylbenzoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine 0.173 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. After this mixture was concentrated, the resulting solid was washed with diethyl ether to yield the desired product.

Workup

  1. concentrationAfter this mixture was concentrated
  2. washthe resulting solid was washed with diethyl ether

Sources & evidence

ORD record
ord-461b0cf3ddd24c2aa6266ef37399f24d
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

Loading…