Hydrochloric Acid → N,N-dimethyl-[6-(anthraquinone-2-carbonyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine hydrochloride

HRID 611139Notes

Reaction equation

HRID 611139 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:31][C:8]2[CH2:9][N:10]([C:13]([C:15]3[CH:28]=[CH:27][C:26]4[C:25](=[O:29])[C:24]5[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=5)[C:18](=[O:30])[C:17]=4[CH:16]=3)=[O:14])[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3].[ClH:32]>CO.C(OCC)(=O)C>[ClH:32].[CH3:3][N:2]([CH2:4][C:5]1[O:31][C:8]2[CH2:9][N:10]([C:13]([C:15]3[CH:28]=[CH:27][C:26]4[C:25](=[O:29])[C:24]5[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=5)[C:18](=[O:30])[C:17]=4[CH:16]=3)=[O:14])[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:1]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 19599897N,N-dimethyl-[6-(anthraquinone-2-carbonyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine

Product 1

HCID 19600174N,N-dimethyl-[6-(anthraquinone-2-carbonyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine hydrochloride

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

N,N-Dimethyl-[6-(anthraquinone-2-carbonyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine 0.227 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. After this mixture was concentrated, the resulting solid was recrystallized from diethyl ether-ethanol to yield the desired product.

Workup

  1. concentrationAfter this mixture was concentrated
  2. customthe resulting solid was recrystallized from diethyl ether-ethanol

Sources & evidence

ORD record
ord-b46d223629d840bf9c83f1f44c2d76e3
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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