Hydrochloric Acid → N,N-dimethyl-[5-(anthraquinone-2-carbonyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine hydrochloride

HRID 611142Notes

Reaction equation

HRID 611142 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14]([C:16]3[CH:29]=[CH:28][C:27]4[C:26](=[O:30])[C:25]5[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=5)[C:19](=[O:31])[C:18]=4[CH:17]=3)=[O:15])[CH2:8][C:7]=2[CH:6]=1)[CH3:3].[ClH:32]>CO.C(OCC)(=O)C>[ClH:32].[CH3:3][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14]([C:16]3[CH:29]=[CH:28][C:27]4[C:26](=[O:30])[C:25]5[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=5)[C:19](=[O:31])[C:18]=4[CH:17]=3)=[O:15])[CH2:8][C:7]=2[CH:6]=1)[CH3:1]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 19599976N,N-dimethyl-[5-(anthraquinone-2-carbonyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine

Product 1

HCID 19599975N,N-dimethyl-[5-(anthraquinone-2-carbonyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine hydrochloride

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

N,N-Dimethyl-[5-(anthraquinone-2-carbonyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine 0.197 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. After this mixture was concentrated, the resulting crystal was washed with diethyl ether to yield the desired product.

Workup

  1. concentrationAfter this mixture was concentrated
  2. washthe resulting crystal was washed with diethyl ether

Sources & evidence

ORD record
ord-b1e7e6e3de7948219f51bc1cf9cb5730
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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