Hydrochloric Acid → HCID 19599894, compound

HRID 611156Notes

Reaction equation

HRID 611156 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:29][C:8]2[CH2:9][N:10]([C:13]([C:15]3[CH:20]=[CH:19][C:18](/[CH:21]=[CH:22]/[C:23]4[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=4)=[CH:17][CH:16]=3)=[O:14])[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3].[ClH:30]>CO.C(OCC)(=O)C>[ClH:30].[CH3:1][N:2]([CH2:4][C:5]1[O:29][C:8]2[CH2:9][N:10]([C:13]([C:15]3[CH:16]=[CH:17][C:18](/[CH:21]=[CH:22]/[C:23]4[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=4)=[CH:19][CH:20]=3)=[O:14])[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 19599885HCID 19599885, compound

Product 1

HCID 19599894HCID 19599894, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

(E)-N,N-Dimethyl-[6-(4-stilbenecarbonyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine 0.153 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. This mixture was concentrated; the resulting solid was washed with diethyl ether to yield the desired product.

Workup

  1. concentrationThis mixture was concentrated
  2. washthe resulting solid was washed with diethyl ether

Sources & evidence

ORD record
ord-2579057d46294c2a84234524e744758d
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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