Hydrochloric Acid → HCID 19600022, compound

HRID 611192Notes

Reaction equation

HRID 611192 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:26][C:8]2[CH2:9][N:10]([C:13](=[O:25])[CH2:14][CH2:15][CH2:16][CH2:17][S:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3].[ClH:27]>CO.C(OCC)(=O)C>[ClH:27].[CH3:1][N:2]([CH2:4][C:5]1[O:26][C:8]2[CH2:9][N:10]([C:13](=[O:25])[CH2:14][CH2:15][CH2:16][CH2:17][S:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 19600008HCID 19600008, compound

Product 1

HCID 19600022HCID 19600022, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

1-(2-Dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)-5-phenylthiopentan-1-one 0.247 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. After this mixture was concentrated, the resulting product was recrystallized from diethyl ether-ethanol to yield the desired product.

Workup

  1. concentrationAfter this mixture was concentrated
  2. customthe resulting product was recrystallized from diethyl ether-ethanol

Sources & evidence

ORD record
ord-29b77fe1afcf4689b580ddf75897d5c5
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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