Hydrochloric Acid → HCID 19599924, compound

HRID 611194Notes

Reaction equation

HRID 611194 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14](=[O:26])[CH2:15][CH2:16][CH2:17][CH2:18][S:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[CH2:8][C:7]=2[CH:6]=1)[CH3:3].[ClH:27]>CO.C(OCC)(=O)C>[ClH:27].[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14](=[O:26])[CH2:15][CH2:16][CH2:17][CH2:18][S:19][C:20]3[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=3)[CH2:8][C:7]=2[CH:6]=1)[CH3:3]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 19599925HCID 19599925, compound

Product 1

HCID 19599924HCID 19599924, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

1-(2-Dimethylaminomethyl-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl)-5-phenylthiopentan-1-one 0.224 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. After this mixture was concentrated, diethyl ether was added; the resulting solid was filtered and washed with diethyl ether to yield the desired product.

Workup

  1. concentrationAfter this mixture was concentrated
  2. additiondiethyl ether was added
  3. filtrationthe resulting solid was filtered
  4. washwashed with diethyl ether

Sources & evidence

ORD record
ord-cb2d9e3dfb2d464a9b6bef5b75deb605
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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