Hydrochloric Acid → HCID 19600253, compound

HRID 611238Notes

Reaction equation

HRID 611238 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([N:15]2[CH2:20][CH2:19][C:18]3[CH:21]=[C:22]([CH2:24][N:25]([CH3:27])[CH3:26])[O:23][C:17]=3[CH2:16]2)=[O:14])=[CH:4][CH:3]=1.Cl>CO.C(OCC)(=O)C>[ClH:1].[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([N:15]2[CH2:20][CH2:19][C:18]3[CH:21]=[C:22]([CH2:24][N:25]([CH3:27])[CH3:26])[O:23][C:17]=3[CH2:16]2)=[O:14])=[CH:4][CH:3]=1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 19600171HCID 19600171, compound

Product 1

HCID 19600253HCID 19600253, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

6-(4-Chlorophenyl)-1-(2-dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)hexan-1-one 0.528 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. This solution was concentrated and washed with diethyl ether to yield the desired product.

Workup

  1. concentrationThis solution was concentrated
  2. washwashed with diethyl ether

Sources & evidence

ORD record
ord-82368257de9b48af9789f51a23f1f6f6
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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