Hydrochloric Acid → HCID 19600200, compound

HRID 611299Notes

Reaction equation

HRID 611299 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14](=[O:31])[C:15]3[CH:20]=[CH:19][C:18]([C:21](=[O:30])[C:22]4[CH:27]=[CH:26][CH:25]=[C:24]([Cl:28])[C:23]=4[Cl:29])=[CH:17][CH:16]=3)[CH2:8][C:7]=2[CH:6]=1)[CH3:3].Cl>CO.C(OCC)(=O)C>[ClH:28].[CH3:3][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14](=[O:31])[C:15]3[CH:16]=[CH:17][C:18]([C:21](=[O:30])[C:22]4[CH:27]=[CH:26][CH:25]=[C:24]([Cl:28])[C:23]=4[Cl:29])=[CH:19][CH:20]=3)[CH2:8][C:7]=2[CH:6]=1)[CH3:1]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 19599929HCID 19599929, compound

Product 1

HCID 19600200HCID 19600200, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

N,N-Dimethyl-[5-[4-(2,3-dichlorobenzoyl)benzoyl]-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine 0.256 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. This mixture was then concentrated and washed with diethyl ether to yield the desired product.

Workup

  1. concentrationThis mixture was then concentrated
  2. washwashed with diethyl ether

Sources & evidence

ORD record
ord-a91a4ea9f85f43f786b9d5377c574ec3
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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