Hydrochloric Acid → HCID 67586773, compound

HRID 611311Notes

Reaction equation

HRID 611311 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:30][C:8]2[CH2:9][N:10]([C:13]([C:15]3[CH:29]=[CH:28][C:18](/[CH:19]=[CH:20]\[C:21]4[CH:26]=[CH:25][C:24]([Cl:27])=[CH:23][CH:22]=4)=[CH:17][CH:16]=3)=[O:14])[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3].Cl>CO.C(OCC)(=O)C>[ClH:27].[CH3:1][N:2]([CH2:4][C:5]1[O:30][C:8]2[CH2:9][N:10]([C:13]([C:15]3[CH:29]=[CH:28][C:18](/[CH:19]=[CH:20]\[C:21]4[CH:22]=[CH:23][C:24]([Cl:27])=[CH:25][CH:26]=4)=[CH:17][CH:16]=3)=[O:14])[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 67586076HCID 67586076, compound

Product 1

HCID 67586773HCID 67586773, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

(Z)-N,N-dimethyl-[6-(4-chlorostilbene-4'-carbonyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine 0.348 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. This mixture was then concentrated and washed with diethyl ether to yield the desired product.

Workup

  1. concentrationThis mixture was then concentrated
  2. washwashed with diethyl ether

Sources & evidence

ORD record
ord-719513eb88554ae8bbaf6c84d4b1c263
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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