Hydrochloric Acid → HCID 67586969, compound

HRID 611316Notes

Reaction equation

HRID 611316 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14]([C:16]3[CH:30]=[CH:29][C:19](/[CH:20]=[CH:21]\[C:22]4[CH:27]=[CH:26][C:25]([Cl:28])=[CH:24][CH:23]=4)=[CH:18][CH:17]=3)=[O:15])[CH2:8][C:7]=2[CH:6]=1)[CH3:3].Cl>CO.C(OCC)(=O)C>[ClH:28].[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14]([C:16]3[CH:30]=[CH:29][C:19](/[CH:20]=[CH:21]\[C:22]4[CH:23]=[CH:24][C:25]([Cl:28])=[CH:26][CH:27]=4)=[CH:18][CH:17]=3)=[O:15])[CH2:8][C:7]=2[CH:6]=1)[CH3:3]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 67586631HCID 67586631, compound

Product 1

HCID 67586969HCID 67586969, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

(Z)-N,N-Dimethyl-[5-(4-chlorostilbene-4'-carbonyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine 0.134 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. This mixture was concentrated and washed with diethyl ether to yield the desired product.

Workup

  1. concentrationThis mixture was concentrated
  2. washwashed with diethyl ether

Sources & evidence

ORD record
ord-5c2705b9e34d4a15846bc6c68ea7d62c
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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