Hydrochloric Acid → HCID 67585255, compound

HRID 611320Notes

Reaction equation

HRID 611320 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14]([C:16]3[CH:30]=[CH:29][C:19](/[CH:20]=[CH:21]\[C:22]4[CH:27]=[CH:26][CH:25]=[C:24]([Cl:28])[CH:23]=4)=[CH:18][CH:17]=3)=[O:15])[CH2:8][C:7]=2[CH:6]=1)[CH3:3].Cl>CO.C(OCC)(=O)C>[ClH:28].[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14]([C:16]3[CH:30]=[CH:29][C:19](/[CH:20]=[CH:21]\[C:22]4[CH:27]=[CH:26][CH:25]=[C:24]([Cl:28])[CH:23]=4)=[CH:18][CH:17]=3)=[O:15])[CH2:8][C:7]=2[CH:6]=1)[CH3:3]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 67585256HCID 67585256, compound

Product 1

HCID 67585255HCID 67585255, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

(Z)-N,N-dimethyl-[5-(3-chlorostilbene-4'-carbonyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine 0.275 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. This mixture was concentrated to yield the desired product.

Workup

  1. concentrationThis mixture was concentrated

Sources & evidence

ORD record
ord-0b87778b912545c5a7f89f9b935e0564
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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