Hydrochloric Acid → HCID 67585908, compound

HRID 611322Notes

Reaction equation

HRID 611322 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:30][C:8]2[CH2:9][N:10]([C:13]([C:15]3[CH:29]=[CH:28][C:18](/[CH:19]=[CH:20]\[C:21]4[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=4[Cl:27])=[CH:17][CH:16]=3)=[O:14])[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3].Cl>CO.C(OCC)(=O)C>[ClH:27].[CH3:1][N:2]([CH2:4][C:5]1[O:30][C:8]2[CH2:9][N:10]([C:13]([C:15]3[CH:29]=[CH:28][C:18](/[CH:19]=[CH:20]\[C:21]4[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=4[Cl:27])=[CH:17][CH:16]=3)=[O:14])[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 67585456HCID 67585456, compound

Product 1

HCID 67585908HCID 67585908, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

(Z)-N,N-Dimethyl-[6-(2-chlorostilbene-4'-carbonyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine 0.602 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. This mixture was concentrated to yield the desired product.

Workup

  1. concentrationThis mixture was concentrated

Sources & evidence

ORD record
ord-e0c5ead926d94bf2a5458eaa84515b9d
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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