HCID 67585518, compound → HCID 67585517, compound

HRID 611324Notes

Reaction equation

HRID 611324 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14]([C:16]3[CH:30]=[CH:29][C:19](/[CH:20]=[CH:21]\[C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=4[Cl:28])=[CH:18][CH:17]=3)=[O:15])[CH2:8][C:7]=2[CH:6]=1)[CH3:3]>CO.Cl.C(OCC)(=O)C>[ClH:28].[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14]([C:16]3[CH:30]=[CH:29][C:19](/[CH:20]=[CH:21]\[C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=4[Cl:28])=[CH:18][CH:17]=3)=[O:15])[CH2:8][C:7]=2[CH:6]=1)[CH3:3]

Participants

5

Reactant 1

HCID 67585518HCID 67585518, compound

Product 1

HCID 67585517HCID 67585517, compound

Reagents, catalysts & solvents 3

HCID 313Hydrochloric AcidSolventHCID 887MethanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

(Z)-N,N-Dimethyl-[5-(2-chlorostilbene-4'-carbonyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine 0.304 g was dissolved in 2 ml of methanol; solution of in hydrogen chloride in ethyl acetate was added in excess, followed by stirring. This mixture was concentrated to yield the desired product.

Workup

  1. concentrationThis mixture was concentrated

Sources & evidence

ORD record
ord-79248be383e544b9a39ff9f221c3f591
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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