Hydrochloric Acid → HCID 19599950, compound

HRID 611357Notes

Reaction equation

HRID 611357 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:29][C:8]2[CH2:9][N:10]([C:13](=[O:28])[C:14]3[CH:19]=[CH:18][C:17]([O:20][CH2:21][C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=4)=[CH:16][CH:15]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3].[ClH:30]>CO.C(OCC)(=O)C>[ClH:30].[CH3:3][N:2]([CH2:4][C:5]1[O:29][C:8]2[CH2:9][N:10]([C:13](=[O:28])[C:14]3[CH:19]=[CH:18][C:17]([O:20][CH2:21][C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=4)=[CH:16][CH:15]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:1]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 19599951HCID 19599951, compound

Product 1

HCID 19599950HCID 19599950, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

N,N-Dimethyl-[6-(4-benzyloxybenzoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine 0.470 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. This mixture was concentrated, and recrystallized from ethanol-diethyl ether to yield the desired product.

Workup

  1. concentrationThis mixture was concentrated
  2. customrecrystallized from ethanol-diethyl ether

Sources & evidence

ORD record
ord-e85528c7d30045a2ad724c52c9d91317
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

Loading…