Methanol → HCID 19598113, compound

HRID 611723Notes

Reaction equation

HRID 611723 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:27][CH3:28])=[C:6]([C:25]=1[CH3:26])[C:7]([C:9]1[C:14]([CH3:15])=[CH:13][C:12]([O:16][CH3:17])=[C:11]([O:18]C(=O)CC)[C:10]=1[O:23][CH3:24])=[O:8].C(=O)([O-])[O-].[K+].[K+].CO>O>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:27][CH3:28])=[C:6]([C:25]=1[CH3:26])[C:7]([C:9]1[C:14]([CH3:15])=[CH:13][C:12]([O:16][CH3:17])=[C:11]([OH:18])[C:10]=1[O:23][CH3:24])=[O:8]

Participants

5

Reactant 3

HCID 887MethanolHCID 11430Potassium CarbonateHCID 19598101HCID 19598101, compound

Product 1

HCID 19598113HCID 19598113, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

A mixture of 66A (6.65 g), potassium carbonate (7.0 g), water (50 ml) and methanol (100 ml) is heated to reflux for 3 hours. Upon cooling to room temperature water is added. The reaction mixture is filtered and the filtrate is acidified with concentrated hydrochloric acid. The solid material is collected and used without further purification.

Workup

  1. temperatureis heated
  2. temperatureto reflux for 3 hours
  3. additionis added
  4. filtrationThe reaction mixture is filtered
  5. customThe solid material is collected
  6. customused without further purification

Sources & evidence

ORD record
ord-bbe46ee6f7564ed5b3b090e5fd62b9c0
Source dataset
uspto-grants-1999_12
Patent number
US06001883

Reaction notes

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