反应详情

O-(2-hydroxy-3-piperidino-propyl)-hydroxylamine (1,74 g, 0,01 mol) was dissolved in 25 ml abs. chloroform and under stirring, 0,98 ml (0,01 mol) isopropyl isocyanate was added. The reaction was monitored by chromatography. At the end of the reaction the solution was evaporated and the oily residue purified by column chromatography. The oil thus obtained was crystallized with methanol-ether.

1. customAt the end of the reaction the solution
2. customwas evaporated
3. customthe oily residue purified by column chromatography
4. customThe oil thus obtained
5. customwas crystallized with methanol-ether