Toluene → HCID 14459515, compound

HRID 611965Notes

Reaction equation

[F:1][S:2]([O:5][CH3:6])(=[O:4])=[O:3].[CH3:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([N:15]([S:32]([C:35]2[CH:40]=[CH:39][C:38]([CH2:41][CH2:42][C:43]([O:45][N:46]3[C:50](=[O:51])[CH2:49][CH2:48][C:47]3=[O:52])=[O:44])=[CH:37][CH:36]=2)(=[O:34])=[O:33])[C:16]([C:18]2[C:19]3[C:24]([N:25]=[C:26]4[C:31]=2[CH:30]=[CH:29][CH:28]=[CH:27]4)=[CH:23][CH:22]=[CH:21][CH:20]=3)=[O:17])=[CH:11][CH:10]=1.C1(C)C=CC=CC=1>ClCCl>[F:1][S:2]([O-:5])(=[O:4])=[O:3].[CH3:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([N:15]([S:32]([C:35]2[CH:40]=[CH:39][C:38]([CH2:41][CH2:42][C:43]([O:45][N:46]3[C:50](=[O:51])[CH2:49][CH2:48][C:47]3=[O:52])=[O:44])=[CH:37][CH:36]=2)(=[O:34])=[O:33])[C:16]([C:18]2[C:31]3[C:26]([N+:25]([CH3:6])=[C:24]4[C:19]=2[CH:20]=[CH:21][CH:22]=[CH:23]4)=[CH:27][CH:28]=[CH:29][CH:30]=3)=[O:17])=[CH:11][CH:10]=1

Participants

Conditions

Temperature: -20 °C

Procedure

0.4 ml of methyl fluorosulfonate is added at -20° C. to 1.27 g of (5) in 60 ml of dichloromethane. The mixture is left to stir at -20° C. for 2 hours and to reach room ##STR17## temperature overnight. Addition of toluene results in precipitation of a yellow solid which is filtered off with suction and dried in vacuo.

Workup

waitThe mixture is left
custom##STR17## temperature overnight
customresults in precipitation of a yellow solid which
filtrationis filtered off with suction
customdried in vacuo

Sources & evidence

ORD record: ord-fc400cb87bae4240bd8449e127d99e1a
Source dataset: uspto-grants-1999_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06002007

Reaction notes

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