Benzaldehyde → HCID 54681217, compound

HRID 613067Notes

Reaction equation

HRID 613067 reaction equation
[OH:1][C:2]1[CH:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[O:5][C:4](=[O:14])[CH:3]=1.[CH:15](=O)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.[C:23]1([SH:29])[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1.N1CCCCC1>C(O)(=O)C.C(O)C>[OH:1][C:2]1[CH:7]=[C:6]([C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=2)[O:5][C:4](=[O:14])[C:3]=1[CH:15]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[S:29][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

Participants

7

Reactant 4

HCID 240BenzaldehydeHCID 7969ThiophenolHCID 8082PiperidineHCID 546956304-Hydroxy-6-phenyl-2H-pyran-2-one

Product 1

HCID 54681217HCID 54681217, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 702EthanolSolvent

Procedure

The title compound was prepared by Method E using 4-hydroxy-6-phenyl-2H-pyran-2-one (1.00 g, 5.31 mmol), ethanol (10 mL), benzaldehyde (0.593 mL, 5.84 mmol), thiophenol (1.40 mL, 13.8 mmol), piperdine (0.5 mL), acetic acid (0.5 mL). m.p. dec. >220° C.; 1H NMR (400 MHz, DMSO-d6) δ5.80 (s, 1 H), 6.70 (s, 1 H), 7.23 (m, 8H), 7.54 (m, 4 H), 7.74 (m, 2 H).

Workup

  1. custom>220° C.

Sources & evidence

ORD record
ord-57058f67e19e479a8956e8386986b113
Source dataset
uspto-grants-1999_12
Patent number
US06005103

Reaction notes

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