Potassium Cyanide → 4-Ethoxybenzene-1-carbonyl cyanide

HRID 614032Notes

Reaction equation

HRID 614032 reaction equation
[CH2:1]([O:3][C:4]1[CH:12]=[CH:11][C:7]([C:8](Cl)=[O:9])=[CH:6][CH:5]=1)[CH3:2].[C-:13]#[N:14].[K+]>[Cu]C#N>[CH2:1]([O:3][C:4]1[CH:12]=[CH:11][C:7]([C:8]([C:13]#[N:14])=[O:9])=[CH:6][CH:5]=1)[CH3:2]

Participants

4

Reactant 2

HCID 9032Potassium CyanideHCID 1400594-Ethoxybenzoyl Chloride

Product 1

HCID 233362744-Ethoxybenzene-1-carbonyl cyanideYield 94.5%

Reagents, catalysts & solvents 1

HCID 178418546HCID 178418546, compoundCatalyst

Procedure

In the manner described above, 184 g (1 mol) of p-ethoxybenzoyl chloride, 62.5 g (0.96 mol) of potassium cyanide and 3.6 g (0.04 mol) of copper(I) cyanide were reacted with one another at 215° C. After working up, 159 g (91% of theory) of p-ethoxybenzoyl cyanide were obtained; melting point 43° C.

Workup

  1. customwere reacted with one another at 215° C

Sources & evidence

ORD record
ord-7a7d4285c3a8478c8cabc3b9d3f37da6
Source dataset
uspto-grants-1979_03
Patent number
US04143068

Reaction notes

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