N,N-Dimethylethylenediamine → HCID 23349880, compound

HRID 614316Notes

Reaction equation

HRID 614316 reaction equation
CS[C:3]1[N:4]=[N:5][CH:6]=[CH:7][N:8]=1.[CH3:9][N:10]([CH2:12][CH2:13][NH2:14])[CH3:11]>C(O)(C)C>[CH3:9][N:10]([CH3:11])[CH2:12][CH2:13][NH:14][C:3]1[N:4]=[N:5][CH:6]=[CH:7][N:8]=1

Participants

4

Reactant 2

HCID 66053N,N-DimethylethylenediamineHCID 3218393-(Methylsulfanyl)-1,2,4-triazine

Product 1

HCID 23349880HCID 23349880, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

3-Methylthio-1,2,4-triazine (19.1 g., 0.15 mole) and unsym-dimethylethylene diamine (35.2 g., 0.40 mole) are dissolved in 100 ml of isopropyl alcohol and the mixture is heated under reflux in a nitrogen atmosphere for five days. The solvent is removed under reduced pressure and the residue is distilled at 0.5 mm of Hg. 3-(2-Dimethylaminoethylamino)-1,2,4-triazine is collected at 168°-169° C.

Workup

  1. temperaturethe mixture is heated
  2. temperatureunder reflux in a nitrogen atmosphere for five days
  3. customThe solvent is removed under reduced pressure
  4. distillationthe residue is distilled at 0.5 mm of Hg
  5. custom3-(2-Dimethylaminoethylamino)-1,2,4-triazine is collected at 168°-169° C.

Sources & evidence

ORD record
ord-7240f77f4a1844c3a3019521c7354557
Source dataset
uspto-grants-1979_03
Patent number
US04144338

Reaction notes

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