反应详情

3-Methylthio-1,2,4-triazine (19.1 g., 0.15 mole) and unsym-dimethylethylene diamine (35.2 g., 0.40 mole) are dissolved in 100 ml of isopropyl alcohol and the mixture is heated under reflux in a nitrogen atmosphere for five days. The solvent is removed under reduced pressure and the residue is distilled at 0.5 mm of Hg. 3-(2-Dimethylaminoethylamino)-1,2,4-triazine is collected at 168°-169° C.

1. temperaturethe mixture is heated
2. temperatureunder reflux in a nitrogen atmosphere for five days
3. customThe solvent is removed under reduced pressure
4. distillationthe residue is distilled at 0.5 mm of Hg
5. custom3-(2-Dimethylaminoethylamino)-1,2,4-triazine is collected at 168°-169° C.