Benzyl Chloride → 2-Methyl-3-nitro-5-tert.-butylphenyl benzyl ether

HRID 614842Notes

Reaction equation

HRID 614842 reaction equation
[CH3:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([C:11]([CH3:14])([CH3:13])[CH3:12])=[CH:4][C:3]=1[OH:15].[CH2:16](Cl)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O>[CH2:16]([O:15][C:3]1[CH:4]=[C:5]([C:11]([CH3:12])([CH3:14])[CH3:13])[CH:6]=[C:7]([N+:8]([O-:10])=[O:9])[C:2]=1[CH3:1])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

5

Reactant 3

HCID 7503Benzyl ChlorideHCID 11430Potassium CarbonateHCID 21327303HCID 21327303, compound

Product 1

HCID 213273062-Methyl-3-nitro-5-tert.-butylphenyl benzyl ether

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

This is obtained, by reacting 2-methyl-3-nitro-5-tert.-butylphenol with benzyl chloride in dimethylformamide in the presence of potassium carbonate at 80° C., in the form of yellowish crystals; m.p. 77°-79° C.

Workup

  1. customThis is obtained
  2. customat 80° C.

Sources & evidence

ORD record
ord-f7b781288c5646b89f08a473b69649d4
Source dataset
uspto-grants-1979_03
Patent number
US04146630

Reaction notes

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