Hydrochloric Acid → HCID 70479528, compound

HRID 615197Notes

Reaction equation

HRID 615197 reaction equation
[CH2:1]([O:3][C@@H:4]1[C@@H:21]([OH:22])[CH2:20][C@@:19]2([CH3:23])[C@@H:6]([CH2:7][CH2:8][C@@H:9]3[C@@H:18]2[C@H:17]([NH:24][CH2:25][CH2:26][CH:27]([CH3:29])[CH3:28])[CH2:16][C@@:14]2([CH3:15])[C@H:10]3[CH2:11][CH2:12][C@@H:13]2[C:30]([O:32][CH3:33])=[O:31])[CH2:5]1)[CH3:2].O.[ClH:35]>>[ClH:35].[CH2:1]([O:3][C@@H:4]1[C@@H:21]([OH:22])[CH2:20][C@@:19]2([CH3:23])[C@@H:6]([CH2:7][CH2:8][C@@H:9]3[C@@H:18]2[C@H:17]([NH:24][CH2:25][CH2:26][CH:27]([CH3:28])[CH3:29])[CH2:16][C@@:14]2([CH3:15])[C@H:10]3[CH2:11][CH2:12][C@@H:13]2[C:30]([O:32][CH3:33])=[O:31])[CH2:5]1)[CH3:2]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 962WaterHCID 70479529HCID 70479529, compound

Product 1

HCID 70479528HCID 70479528, compoundYield 0.56%

Procedure

Methyl 3α-ethoxy-2β-hydroxy-11α-(3-methylbutylamino)-5α-androstane-17β carboxylate (100 mg) was dissolved in 0.0987M HCl solution (2.2 ml) as far as possible. The mixture was made up to 15 g the addition of water and filtered. The residue was collected, dried and weighed. This gave a 0.56% solution with respect to free base, pH 2.2.

Workup

  1. filtrationfiltered
  2. customThe residue was collected
  3. customdried

Sources & evidence

ORD record
ord-59d85bf2e0c64eec99dce727a971c5f8
Source dataset
uspto-grants-1985_02
Patent number
US04497805

Reaction notes

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