Sodium Hydroxide → 1,3,5-Triazino(1,2-a)benzimidazol-4(1H)-one, 2,3-dihydro-2,2-dimethyl-3-propyl-

HRID 615283Notes

Reaction equation

HRID 615283 reaction equation
[CH3:1][C:2]1([CH3:25])[N:10]([CH2:11][CH2:12][CH3:13])[C:9](=[O:14])[N:8]2[C:4]([N:5](C(NCCC)=O)[C:6]3[CH:18]=[CH:17][CH:16]=[CH:15][C:7]=32)=[N:3]1.[OH-].[Na+]>C1COCC1>[CH3:25][C:2]1([CH3:1])[N:10]([CH2:11][CH2:12][CH3:13])[C:9](=[O:14])[N:8]2[C:4](=[N:5][C:6]3[CH:18]=[CH:17][CH:16]=[CH:15][C:7]=32)[NH:3]1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 13454039HCID 13454039, compound

Product 1

HCID 1591041,3,5-Triazino(1,2-a)benzimidazol-4(1H)-one, 2,3-dihydro-2,2-dimethyl-3-propyl-

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The title compound was prepared by hydrolysis of the precursor compound of Example 3 in the presence of 10% aqueous sodium hydroxide and THF employing the method of paragraph 2, Example 1. The product was crystallized from acetone to give colorless prisms, mp 170° C. (dec). The confirmatory elemental analysis is shown in Table III.

Workup

  1. customThe product was crystallized from acetone
  2. customto give colorless prisms, mp 170° C. (dec)

Sources & evidence

ORD record
ord-b86ccace22aa47c595405d470099ef1c
Source dataset
uspto-grants-1985_02
Patent number
US04498920

Reaction notes

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