2-Amino-6-methoxybenzothiazole → HCID 70487283, compound

HRID 615441Notes

Reaction equation

HRID 615441 reaction equation
[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[CH:7][C:5]=2[N:6]=1.[C:13]([O:19]C[I:21])(=[O:18])[C:14]([CH3:17])([CH3:16])[CH3:15].O1CCOC[CH2:23]1>>[IH:21].[CH3:12][O:11][C:9]1[CH:8]=[CH:7][C:5]2[N:6]([CH:15]([CH3:23])[C:14]([CH3:17])([CH3:16])[C:13]([OH:19])=[O:18])[C:2](=[NH:1])[S:3][C:4]=2[CH:10]=1

Participants

4

Reactant 3

HCID 156302-Amino-6-methoxybenzothiazoleHCID 312751,4-DioxaneHCID 104401Iodomethyl pivalate

Product 1

HCID 70487283HCID 70487283, compound

Procedure

A solution of 2-amino-6-methoxy benzothiazole (8.5 g) and iodomethyl pivalate (11.5 g) in dry dioxan (120 ml) was stored at room temperature for 7 days. The resulting solid was collected and dried to give the sub-title product (14 g), mp 191°-3° as a hemi-solvate with dioxan (n.m.r.).

Workup

  1. customThe resulting solid was collected
  2. customdried

Sources & evidence

ORD record
ord-5616e278f0c847bea8590786c702472c
Source dataset
uspto-grants-1985_02
Patent number
US04499269

Reaction notes

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