Hydrochloric Acid → HCID 23318282, compound

HRID 615656Notes

Reaction equation

HRID 615656 reaction equation
C([NH:4][C:5]1[CH:10]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[C:8]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[CH:7][C:6]=1[OH:32])(=O)C.[ClH:33]>C(O)C>[ClH:33].[NH2:4][C:5]1[CH:10]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[C:8]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[CH:7][C:6]=1[OH:32]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 20257269N-[5-tert-Butyl-4-(hexadecyloxy)-2-hydroxyphenyl]acetamide

Product 1

HCID 23318282HCID 23318282, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 23.0 g of 2-acetylamino-4-tert-butyl-5-hexadecyloxyphenol, 120 ml of ethanol and 96 ml of 35% hydrochloric acid was refluxed with stirring for 5 hours. The reaction solution was cooled to precipitate crystals. The crystals were collected by filtration. 23.2 g of 2-amino-4-tert-butyl-5-hexadecyloxyphenol hydrochloride was obtained.

Workup

  1. temperaturewas refluxed
  2. temperatureThe reaction solution was cooled
  3. customto precipitate crystals
  4. filtrationThe crystals were collected by filtration

Sources & evidence

ORD record
ord-514f93dd219045f089d63056bf10c5d0
Source dataset
uspto-grants-1985_02
Patent number
US04500626

Reaction notes

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