Hydrochloric Acid → HCID 20066230, compound

HRID 615727Notes

Reaction equation

HRID 615727 reaction equation
[Na].[C:2]([CH:5]([C:11]([CH3:20])([CH3:19])[CH:12](Cl)[CH2:13][C:14]([Cl:17])([Cl:16])Cl)[C:6]([O:8][CH2:9][CH3:10])=[O:7])(=[O:4])[CH3:3].Cl>C(O)C>[C:2]([C:5]1([C:6]([O:8][CH2:9][CH3:10])=[O:7])[C:11]([CH3:19])([CH3:20])[CH:12]1[CH:13]=[C:14]([Cl:16])[Cl:17])(=[O:4])[CH3:3]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 5360545SodiumHCID 13646833Ethyl 2-acetyl-4,6,6,6-tetrachloro-3,3-dimethylhexanoate

Product 1

HCID 20066230HCID 20066230, compoundYield 88%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Sodium (0.5 g) was dissolved in 37 ml of absolute ethanol, and 2.9 g of ethyl 2-acetyl-4,6,6,6-tetrachloro-3,3-dimethylhexanoate was added thereto. The mixture was stirred at room temperature for 30 minutes and then heated at a temperature of 50° C. for 24 hours with stirring. The mixture was rendered neutral with an ethereal solution of hydrogen chloride, while cooled with ice and the solvent was distilled off. The resulting residue was dissolved in diethyl ether, and the solution was washed with water, dried over anhydrous magnesium sulfate, and distilled to give 2.01 g (88% yield) of ethyl 1-acetyl-2-(2,2-dichlorovinyl)3,3-dimethylcyclopropanecarboxylate.

Workup

  1. temperatureheated at a temperature of 50° C. for 24 hours
  2. stirringwith stirring
  3. temperaturewhile cooled with ice
  4. distillationthe solvent was distilled off
  5. dissolutionThe resulting residue was dissolved in diethyl ether
  6. washthe solution was washed with water
  7. dry with materialdried over anhydrous magnesium sulfate
  8. distillationdistilled

Sources & evidence

ORD record
ord-7de73356dcc549468e82137a0f4552eb
Source dataset
uspto-grants-1985_02
Patent number
US04500733

Reaction notes

Loading…