Hydrochloric Acid → HCID 86739935, compound

HRID 615830Notes

Reaction equation

HRID 615830 reaction equation
[ClH:1].[CH2:2]([NH:4][CH2:5][CH3:6])[CH3:3].[P:7]([OH:10])([OH:9])[OH:8].[C:11]([OH:15])(=[O:14])[CH:12]=O.Cl>>[OH2:8].[ClH:1].[CH2:2]([N:4]([O:8][P:7]([CH2:12][C:11]([OH:15])=[O:14])([OH:10])=[O:9])[CH2:5][CH3:6])[CH3:3]

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 760Glyoxylic AcidHCID 107909Phosphorous acidHCID 10197650Diethylammonium chloride

Product 1

HCID 86739935HCID 86739935, compound

Procedure

A solution of 16.3 parts by weight of diethylamine hydrochloride, 16.6 parts by weight or orthophosphorous acid, and 29.6 parts by weight of glyoxylic acid (50% aqueous solution) in 50 parts by volume of 18% hydrochloric acid is heated to reflux for 18 hours. Volatile material is then removed by vacuum distillation and the residual oil triturated with acetone to remove impurities. In this way, there are obtained 28 parts by weight of 2-diethylaminophosphonoacetic acid hydrochloride monohydrate having the following analysis by weight:

Workup

  1. temperatureto reflux for 18 hours
  2. customVolatile material is then removed by vacuum distillation
  3. customthe residual oil triturated with acetone
  4. customto remove impurities

Sources & evidence

ORD record
ord-c39b88af050d4ec89d7f22ca2b90518c
Source dataset
uspto-grants-1985_02
Patent number
US04501667

Reaction notes

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