Acetyl chloride → HCID 13652438, compound

HRID 615878Notes

Reaction equation

HRID 615878 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][CH2:9][C:10]2[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=2)=[CH:4][CH:3]=1.[C:16](Cl)(=[O:18])[CH3:17]>C(N(CC)CC)C>[N:12]1[CH:13]=[CH:14][CH:15]=[C:10]([CH2:9][N:8]([C:5]2[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=2)[C:16](=[O:18])[CH3:17])[CH:11]=1

Participants

4

Reactant 2

HCID 6367Acetyl chlorideHCID 28045454-chloro-N-(pyridin-3-ylmethyl)aniline

Product 1

HCID 13652438HCID 13652438, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

N-[(3-pyridyl)methyl]-N-(4-chlorophenyl)acetamide was prepared by reacting 5.0 g. of N-(4-chlorophenyl)-[(3-pyridyl)methyl]amine with 2.0 g. of acetyl chloride in 250 ml. containing 3.0 g. of triethylamine according to the method of Example 11. Weight 1.1 g. M.P. 64°-65° C.

Workup

  1. additioncontaining 3.0 g

Sources & evidence

ORD record
ord-7d573c15305c45d1b1fd9e6b12a67a52
Source dataset
uspto-grants-1985_02
Patent number
US04501746

Reaction notes

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