反应详情

2.37 G. of 1-acetamido-2-nitro-4-thiocyanatobenzene in 10 ml. dimethylformamide is treated, under nitrogen, with 0.38 g. sodium borohydride at 20°-30° C. After one hour at 20°-30° C., 1.6 ml. of chloromethyl methyl ether is added. The mixture is stirred for a further 3 hour period, then diluted with water. The crude product is filtered off and recrystallized from cyclohexane, yielding 1-acetamido-2-nitro-4-methoxymethylthiobenzene.

1. customat 20°-30° C
2. filtrationThe crude product is filtered off
3. customrecrystallized from cyclohexane