Methanol → HCID 20371170, compound

HRID 616113Notes

Reaction equation

HRID 616113 reaction equation
[C:1]([NH:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([CH2:13][C:14]#[CH:15])=[O:12])=[CH:7][C:6]=1[N+:16]([O-])=O)(=[O:3])[CH3:2].CO>[Fe].O>[C:1]([NH:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([CH2:13][C:14]#[CH:15])=[O:12])=[CH:7][C:6]=1[NH2:16])(=[O:3])[CH3:2]

Participants

5

Reactant 2

HCID 887MethanolHCID 20371184HCID 20371184, compound

Product 1

HCID 20371170HCID 20371170, compound

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 962WaterSolvent

Procedure

2 G. of 1-acetamido-2-nitro-4-propargylsulfinylbenzene is treated in a refluxing mixture of 160 ml. methanol and 40 ml. water with 4 g. iron powder (added in two portions) and 1 g. ferrous sulfate for four hours. The mixture is filtered, and the filtrated concentrated. The residue is dissolved in chloroform and washed with water, then the solvent evaporated affording 1-acetamido-2-amino-4-propargylsulfinylbenzene.

Workup

  1. filtrationThe mixture is filtered
  2. concentrationthe filtrated concentrated
  3. dissolutionThe residue is dissolved in chloroform
  4. washwashed with water
  5. customthe solvent evaporated

Sources & evidence

ORD record
ord-0e5371d254754ae79db2eb2e1944e357
Source dataset
uspto-grants-1978_02
Patent number
US04072696

Reaction notes

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