Methanol → HCID 20370997, compound

HRID 616121Notes

Reaction equation

HRID 616121 reaction equation
[CH3:1][O:2][C:3]([NH:5][C:6](=[S:21])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([S:14][CH2:15][CH:16]=[CH2:17])=[CH:10][C:9]=1[N+:18]([O-])=O)=[O:4].CO>[Fe].O>[CH3:1][O:2][C:3]([NH:5][C:6](=[S:21])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([S:14][CH2:15][CH:16]=[CH2:17])=[CH:10][C:9]=1[NH2:18])=[O:4]

Participants

5

Reactant 2

HCID 887MethanolHCID 20371043HCID 20371043, compound

Product 1

HCID 20370997HCID 20370997, compound

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 962WaterSolvent

Procedure

1.5 G. of 1-(3-methoxycarbonyl-2-thioureido)-2-nitro-4-(prop-2-en-1-ylthio)benzene is treated for four hours in a refluxing mixture of 160 ml. methanol and 40 ml. water with 4 g. iron powder (added in two portions) and 1 g. ferrous sulfate. The mixture is filtered, and the filtrate concentrated. The residue is dissolved in chloroform and washed with water, and then the solvent is evaporated affording 1-(3-methoxycarbonyl-2-thioureido)-2-amino-4-(prop-2-en-1-yl-thio)benzene.

Workup

  1. filtrationThe mixture is filtered
  2. concentrationthe filtrate concentrated
  3. dissolutionThe residue is dissolved in chloroform
  4. washwashed with water
  5. customthe solvent is evaporated

Sources & evidence

ORD record
ord-78ef769642ae452d98147d1cccf696db
Source dataset
uspto-grants-1978_02
Patent number
US04072696

Reaction notes

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