Hydrochloric Acid → 4-Phenoxybenzene-1,2-diamine

HRID 616137Notes

Reaction equation

HRID 616137 reaction equation
C([NH:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:7][C:6]=1[NH2:18])(=O)C.Cl>CO>[NH2:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:7][C:6]=1[NH2:18]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 203710941-Acetamido-2-amino-4-phenoxybenzene

Product 1

HCID 106556434-Phenoxybenzene-1,2-diamine

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1-Acetamido-2-amino-4-phenoxybenzene is treated with hydrochloric acid in aqueous methanol to afford 1,2-diamino-4-phenoxybenzene which, in turn, is reacted with methoxycarbonyl isothiocyanate in accordance with the technique set forth in the third paragraph of Example XIV to afford 1,2-bis(3-methoxycarbonyl-2-thioureido)-4-phenoxybenzene.

Sources & evidence

ORD record
ord-bd1c84df3a2d494b9fbf89ce0932367a
Source dataset
uspto-grants-1978_02
Patent number
US04072696

Reaction notes

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