反应详情

To a solution of 27.17 g (0.141 mol) of 8-methoxyisatoic anhydride in 200 mL of ethanol was added a catalytic amount of 4-dimethylaminopyridine and 350 mL of a 1M solution containing 43.0 g (0.350 mol) of p-anisidine. The reaction mixture was stirred and heated under reflux overnight. The reaction flask was then chilled on ice. The precipitate that formed was collected by vacuum filtration and amounted to 34.7 g. An analytical sample (mp 168-169° C.) was obtained by recrystallization from ethanol.

1. temperatureheated
2. temperatureunder reflux overnight
3. temperatureThe reaction flask was then chilled on ice
4. customThe precipitate that formed
5. filtrationwas collected by vacuum filtration
6. customAn analytical sample (mp 168-169° C.) was obtained by recrystallization from ethanol