Magnesium ethanolate → CID 11066066

HRID 617189Notes

Reaction equation

HRID 617189 reaction equation
[C:1]([O:7][CH2:8][CH3:9])(=[O:6])[CH2:2][C:3]([O-:5])=[O:4].[O-]CC.[Mg+2:13].[O-]CC>C1COCC1>[C:1]([O:7][CH2:8][CH3:9])(=[O:6])[CH2:2][C:3]([O-:5])=[O:4].[Mg+2:13].[CH2:8]([O:7][C:1](=[O:6])[CH2:2][C:3]([O-:5])=[O:4])[CH3:9]

Participants

4

Reactant 2

HCID 164963Magnesium ethanolateHCID 3595298Propanedioic acid, monoethyl ester

Product 1

HCID 11066066CID 11066066Yield 95.8%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Magnesium ethyl malonate was prepared as follows: To a stirred THF solution (1 L) of monoethyl malonate (183.18 g, 1.39 mol) was added magnesium ethoxide (79.54 g, 0.70 mol) in several portions. After about 4 hours, the solvent was removed under reduced pressure and the residue was reevaporated with toluene to give magnesium ethyl malonate (190.82 g).

Workup

  1. customMagnesium ethyl malonate was prepared
  2. customthe solvent was removed under reduced pressure
  3. customthe residue was reevaporated with toluene

Sources & evidence

ORD record
ord-1b895215a47345c1a72880cfa768901a
Source dataset
uspto-grants-1999_09
Patent number
US05948786

Reaction notes

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