Hydrochloric Acid → HCID 12252984, compound

HRID 617634Notes

Reaction equation

HRID 617634 reaction equation
[C:1]1([CH3:9])[CH:6]=[CH:5][C:4]([C:7]#[N:8])=[CH:3][CH:2]=1.[ClH:10].[CH2:11]([OH:13])[CH3:12]>>[ClH:10].[CH3:9][C:1]1[CH:6]=[CH:5][C:4]([C:7](=[NH:8])[O:13][CH2:11][CH3:12])=[CH:3][CH:2]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 7724p-Tolunitrile

Product 1

HCID 12252984HCID 12252984, compound

Procedure

Ethyl 4-methylbenzimidate hydrochloride was synthesized in the same manner as in Reference Example 2. That is, p-tolunitrile (25.6 g, 0.219 mol) was treated with hydrogen chloride in ethanol (250 mL) to give 42.3 g (97%) of the target compound as colorless crystals.

Sources & evidence

ORD record
ord-a15031934c624af2a1baceb326ad0335
Source dataset
uspto-grants-1999_09
Patent number
US05948785

Reaction notes

Loading…