反应详情

2',5'-Dimethoxyacetophenone (1.80 g) and indole-3-carboxaldehyde (1.45 g) were dissolved in ethanol (20 ml), and piperidine (0.85 g) was added thereto, followed by heating under reflux for 72 hours. The precipitated crystals were collected by filtration, and the obtained crude crystals were recrystallized from ethanol to give Compound 89 (1.35 g).

1. temperatureby heating
2. temperatureunder reflux for 72 hours
3. filtrationThe precipitated crystals were collected by filtration
4. customthe obtained crude crystals
5. customwere recrystallized from ethanol