HRID618136

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

结构：CC(C)(C)OC(=O)NCC(=O)NC[C@H](NS(=O)(=O)c1ccccc1)C(=O)OC(C)(C)C

HCID86754468

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)[C@H](CNC(=O)CN)NS(=O)(=O)c1ccccc1.O=C(O)C(F)(F)F

HCID86754466

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

CONDITIONS

反应条件

温度: -15 °C

PROCEDURE

实验过程

Protected amide 1-6 (576 mg, 1.26 mmol) was dissolved in 6.3 mL CH2Cl2, cooled to -15° C., and TFA (6.3 mL) was added. After 25 min the reaction was concentrated, providing amine 1-7.

WORKUP

后处理

concentrationAfter 25 min the reaction was concentrated