反应详情

[1-(5-Cyanothiophene-3-ylmethyl)-2-oxopyrrolidin-3-yl]carbamic acid tert-butyl ester (4 g, 13.8 mmol) is added to a solution of 100 mL of EtOAc sat. with HCl gas at 0° C. After 3 hours, the solution is concentrated. The title compound (3.3 g, 13.5 mmol) is obtained as a white solid.

1. concentrationthe solution is concentrated