Formaldehyde → HCID 23044696, compound

HRID 620140Notes

Reaction equation

HRID 620140 reaction equation
[CH2:1]([P:16](=[O:29])([O:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[O:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[P:2](=[O:15])([O:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])[O:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].C=O.[CH2:32](NCC)C>CO>[C:1]([P:2](=[O:15])([O:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])[O:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8])([P:16](=[O:29])([O:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[O:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])=[CH2:32]

Participants

5

Reactant 3

HCID 712FormaldehydeHCID 8021DiethylamineHCID 601065HCID 601065, compound

Product 1

HCID 23044696HCID 23044696, compoundYield 68.3%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

20.20 g (44.0 mmol) of tetra-n-pentyl methylenebisphosphonate, 6.61 g (220.0 mmol) of paraformaldehyde and 3.22 g (64.0 mmol) of diethylamine are combined with the same reactants and the same conditions as described above in Example I. This mixture is then refluxed for 48 hours. After the methanol is eliminated as described above in Example I. 14.08 g of tetra-n-pentyl ethenylidenebisphosphonate is produced as a clear liquid.

Workup

  1. temperatureThis mixture is then refluxed for 48 hours

Sources & evidence

ORD record
ord-2694c32d22aa4e1db1baf50518b7bcb9
Source dataset
uspto-grants-1989_04
Patent number
US04820698

Reaction notes

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