HCID 15617525, compound → HCID 15617526, compound

HRID 620559Notes

Reaction equation

HRID 620559 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][C:9]1[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=1[CH2:11][OH:12]>[O-2].[Mn+2].C(OCC)(=O)C>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][C:9]1[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=1[CH:11]=[O:12]

Participants

4

Reactant 1

HCID 15617525HCID 15617525, compound

Product 1

HCID 15617526HCID 15617526, compound

Reagents, catalysts & solvents 2

HCID 160959Manganese oxideCatalystHCID 8857Ethyl AcetateSolvent

Procedure

To ethyl acetate (150 ml), cooled to 0° C., was added manganese oxide (15 g) followed by 2-(7-bromoheptyl) benzyl alcohol (3.39 g, 1.2 mmoles). The reaction mixture was permitted to warm to room temperature slowly, and stirred for 1 hour. The mixture was then cooled to 0° C. and stirred for 18 hours. Subsequently the mixture was filtered and evaporated to yield the desired product.

Workup

  1. temperatureThe mixture was then cooled to 0° C.
  2. stirringstirred for 18 hours
  3. filtrationSubsequently the mixture was filtered
  4. customevaporated

Sources & evidence

ORD record
ord-6dafa169e2824cf2b11a15e793f8e521
Source dataset
uspto-grants-1989_04
Patent number
US04820719

Reaction notes

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