Magnesium → HCID 178436337, compound

Temperature

80 °C

To a 2 liter three-neck flask equipped with a 500 ml dropping funnel, a reflux condenser, and a stirrer was added 28 g (1.15 mole) of metallic magnesium and it was dried sufficiently by supplying dry nitrogen gas. After that, 50 ml of tetrahydrofuran which had been dried with a molecular sieve 5 A, was dropped into the flask and the contents were stirred vigorously. A solution of 183 g (1.0 mole) of 3-vinylbenzene bromide in 500 ml of dry tetrahydrofuran was dropped little by little over 2 hours. The temperature was maintained at about 80° C. and, after the dropping of the solution, the stirring was continued for further 1 hour as it stands. Thereby obtaining a Grignard reagent (3-vinylphenylmagnesium bromide: formula VII).

1. customTo a 2 liter three-neck flask equipped with a 500 ml
2. customwas dried sufficiently
3. dry with materialAfter that, 50 ml of tetrahydrofuran which had been dried with a molecular sieve 5 A
4. additionwas dropped into the flask

ORD record

ord-e86052188b754f038190ccb62c728389

Source dataset

uspto-grants-1989_04

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US04822934