Triphenylphosphine → 4-(Benzoxazol-2-yl)tolyltriphenylphosphonium bromide

HRID 6211Notes

Reaction equation

HRID 6211 reaction equation
[Br:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[O:10][C:11]3[CH:17]=[CH:16][CH:15]=[CH:14][C:12]=3[N:13]=2)=[CH:5][CH:4]=1.[C:18]1([P:24]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>C1(C)C(C)=CC=CC=1>[Br-:1].[O:10]1[C:11]2[CH:17]=[CH:16][CH:15]=[CH:14][C:12]=2[N:13]=[C:9]1[C:6]1[CH:7]=[CH:8][C:3]([CH3:2])=[C:4]([P+:24]([C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=2)([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH:5]=1

Participants

4

Reactant 2

HCID 11776TriphenylphosphineHCID 110335154-(Benzoxazol-2-yl)benzyl bromide

Product 1

HCID 867444264-(Benzoxazol-2-yl)tolyltriphenylphosphonium bromide

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

A stirred solution of 28.8 g (0.1 mole) of 2-(4-bromomethylphenyl)benzoxazole and 28.8 g (0.1 mole) of triphenylphosphine in xylene is heated at reflux for 19 hours. The product is then isolated by filtration, washed with additional portions of xylene, and dried.

Workup

  1. temperatureat reflux for 19 hours
  2. customThe product is then isolated by filtration
  3. washwashed with additional portions of xylene
  4. customdried

Sources & evidence

ORD record
ord-c3e99be3835445b2abbdee8d3ce15e26
Source dataset
uspto-grants-1993_09
Patent number
US05247042

Reaction notes

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