Hydrochloric Acid → HCID 178518526, compound

HRID 621656Notes

Reaction equation

HRID 621656 reaction equation
[OH:1][C:2]1[N:7]2[N:8]=[CH:9][C:10]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)=[C:6]2[N:5]=[C:4](S)[N:3]=1.[OH-:18].[Na+].OO.Cl>CO>[OH:18][C:4]1[N:3]=[C:2]([OH:1])[N:7]2[N:8]=[CH:9][C:10]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)=[C:6]2[N:5]=1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 784Hydrogen PeroxideHCID 14798Sodium HydroxideHCID 178518553HCID 178518553, compound

Product 1

HCID 178518526HCID 178518526, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a mixture of 4-hydroxy-2-mercapto-8-phenylpyrazolo[1,5-a]-1,3,5-triazine (130 mg), 0.25N sodium hydroxide solution (4 ml) and methanol (3 ml) is with stirring added 30% hydrogen peroxide (1 ml) under ice cooling. The mixture is reacted for one hour, and the reaction mixture is adjusted to pH 1-2 with conc. hydrochloric acid. The resulting precipitate is separated by filtration, washed with water and methanol and dried to give the title compound (25.8 mg).

Workup

  1. customThe mixture is reacted for one hour
  2. customThe resulting precipitate is separated by filtration
  3. washwashed with water and methanol
  4. customdried

Sources & evidence

ORD record
ord-5d385e19d6ba4ae5b4178db81a347141
Source dataset
uspto-grants-1989_04
Patent number
US04824834

Reaction notes

Loading…