Dimethylamine, hydrochloride → HCID 3554384, compound

HRID 622807Notes

Reaction equation

HRID 622807 reaction equation
Cl.[CH3:2][NH:3][CH3:4].[CH3:5][O:6][C:7](=[O:17])[C:8]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[CH:9]O.[Na]>O>[CH3:5][O:6][C:7](=[O:17])[C:8]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[CH:9][N:3]([CH3:4])[CH3:2]

Participants

4

Reactant 2

HCID 10473Dimethylamine, hydrochlorideHCID 70407058HCID 70407058, compound

Product 1

HCID 3554384HCID 3554384, compoundYield 72.2%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

97 weight-parts of dimethylamine hydrochloride are dissolved in 250 weight-parts of water, and 200 weight-parts of sodium 3-hydroxy-2-phenyl acrylic acid methyl ester are added. The mixture is stirred for 2 hours, and the organic phase is separated and distilled. 148 weight-parts of 3-dimethylamino-2-phenyl acrylic acid methyl ester are obtained, corresponding to a yield of 72.2% of the theory.

Workup

  1. additionare added
  2. customthe organic phase is separated
  3. distillationdistilled

Sources & evidence

ORD record
ord-42f29bb6a9ac4b9d87ac01e86138f738
Source dataset
uspto-grants-1988_09
Patent number
US04772711

Reaction notes

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