Acetyl chloride → Bis(1-methylethyl) B-phenylboronate

HRID 622918Notes

Reaction equation

HRID 622918 reaction equation
[C:1]1([Li])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:8]([O:11][B:12](OC(C)C)[O:13][CH:14]([CH3:16])[CH3:15])([CH3:10])[CH3:9].C(Cl)(=O)C>>[C:1]1([B:12]([O:13][CH:14]([CH3:16])[CH3:15])[O:11][CH:8]([CH3:10])[CH3:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 3

HCID 6367Acetyl chlorideHCID 21531Triisopropyl borateHCID 178506676HCID 178506676, compound

Product 1

HCID 569210Bis(1-methylethyl) B-phenylboronate

Procedure

Following the procedure of Example 9, phenyllithium (17 mL, 30.6 mmol) and triisopropoxyborane (5.6 g, 30 mmol) were reacted, and the reaction quenched with acetyl chloride (2.1 mL, 30 mmol) to yield after distillation 5.2 g (25.2 mmol, 84%).

Workup

  1. customwere reacted
  2. customto yield
  3. distillationafter distillation 5.2 g (25.2 mmol, 84%)

Sources & evidence

ORD record
ord-9e6c2d94fac9448b966dfa51d02554bc
Source dataset
uspto-grants-1988_09
Patent number
US04772751

Reaction notes

Loading…