Hydrogen Peroxide → HCID 178511804, compound

HRID 625716Notes

Reaction equation

HRID 625716 reaction equation
[NH2:1][C@H:2]([C:9]([OH:11])=[O:10])[CH2:3][C:4]1[N:8]=[CH:7][NH:6][CH:5]=1.OO.[Ce:14].[N+]([O-])(O)=O>O>[NH2:1][C@H:2]([C:9]([OH:11])=[O:10])[CH2:3][C:4]1[N:8]=[CH:7][NH:6][CH:5]=1.[Ce:14]

Participants

6

Reactant 4

HCID 784Hydrogen PeroxideHCID 944Nitric AcidHCID 23974CeriumHCID 178419078HCID 178419078, compound3×

Product 1

HCID 178511804HCID 178511804, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
40 °C

Procedure

Into a 600 ml glass beaker containing a magnetic stir bar was introduced 500 ml of high purity (HP) water. A 0.715 gm quantity of L-histidine was dissolved in this volume and the solution was heated to about 40° C., forming an alkaline solution. A 10.0 gm quantity of Ce(NO3)3·6(H2O) was added, about pH 6. The molar ratio of L-histidine to cerium ion was 0.2. Then a 10 ml solution containing 1.20 gm of 50% H2O2 (0.75 molar ratio of H2O2 to cerium ion) was added slowly to the cerium and histidine solution mixture. The pH was further adjusted to about 2.1 by the addition of 1N HNO3, thereby forming a clear brown suspension. The product suspension was then washed to remove salts by diafiltration, during which about two turnover volumes of HP water were added, and then concentrated to a final ionic conductivity of about 2.1 mS/cm and a pH of 3.1.

Workup

  1. customforming an alkaline solution
  2. customforming a clear brown suspension
  3. washThe product suspension was then washed
  4. customto remove salts by diafiltration
  5. additionduring which about two turnover volumes of HP water were added
  6. concentrationconcentrated to a final ionic conductivity of about 2.1 mS/cm

Sources & evidence

ORD record
ord-20d54105015f49c89480802afad9d06d
Source dataset
uspto-grants-2016_04
Patent number
US09308265B2

Reaction notes

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