HRID626572

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cc1nc(NC(=O)NC(=O)C(C)(C)C)ccc1Oc1ccnc(NC(=O)OC(C)(C)C)c1

HCID131735227

未命名化合物

PRODUCTS

生成物

结构：Cc1nc(NC(=O)NC(=O)C(C)(C)C)ccc1Oc1ccnc(N)c1

HCID90410520

未命名化合物

收率 98%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6422

未命名化合物

PROCEDURE

实验过程

A mixture of tert-butyl (4-((2-methyl-6-(3-pivaloylureido)pyridin-3-yl)oxy)pyridin-2-yl)carbamate (0.370 g, 0.834 mmol in TFA (5 mL) was stirred at RT for 0.5 h and concentrated to dryness to afford N-((5-((2-aminopyridin-4-yl)oxy)-6-methylpyridin-2-yl)carbamoyl)pivalamide (280 mg, 98%). MS (ESI) m/z: 344.2 (M+H+).

WORKUP

后处理

concentrationconcentrated to dryness