反应详情

The product of step C was dissolved in ethanol (24 ml), 4M NaOH was added (12 ml) and the mixture was stirred at room temperature for two hours. The mixture was acidified with 1M HCl and extracted with ethyl acetate. The organic extract was dried over magnesium sulfate, the solvent was removed under reduced pressure. 2.67 g of a colourless oil were obtained. MS(ESI) m/z=135.0 [M-1]−.

1. extractionextracted with ethyl acetate
2. extractionThe organic extract
3. dry with materialwas dried over magnesium sulfate
4. customthe solvent was removed under reduced pressure